Research Interest:
Immunology - Antibody-mediated regulation of the immune response and microbial immunity.
Training:
1962 - B.S., Colorado State University, Ft. Collins, CO
1964 - M.S., Colorado State University, Ft. Collins, CO
1972 - Ph.D., Montana State University, Bozeman, MT
1972 - 73 - Postdoctoral Teaching Associate, Montana State University, Bozeman, MT
1973 - 74 - Postdoctoral Fellow, Montana State University, Bozeman, MT
Publications: NCBI PubMed search for "D.D. Manning"
van der Heyde, H.C., D.D. Manning, and W.P. Weidanz. 1993. Role of CD4+ T cells in the expansion of the CD4-, CD8- gamma delta T cell subset in spleens of mice during blood-stage malaria. J. Immunol. 151:6311.
van der Heyde, H.C., D. Huszar, C. Woodhouse, D.D. Manning, and W.P. Weidanz. 1994. The resolution of acute malaria in a definitive model of B cell deficiency, the JHD mouse. J. Immunol. 152:4557.
Elloso, M.M., H.C. van der Heyde, J.A. vande Waa, D.D. Manning, and W.P. Weidanz. 1994. Inhibition of Plasmodium falciparum in vitro by human gamma delta T cells. J. Immunol. 153:1187.
van der Heyde, H.C., M.M. Elloso, W.-L. Chang, M. Kaplan, D.D. Manning, and W.P. Weidanz. 1995. Gamma delta T cells function in cell-mediated immunity to acute blood-stage Plasmodium chabaudi adami malaria. J. Immunol. 154:3985.
Yanez, D.M., D.D. Manning, A.J. Cooley, W.P. Weidanz, and H.C. van der Heyde. 1996. Participation of lymphocyte subpopulations in the pathogenesis of experimental murine cerebral malaria. J. Immunol. 157:1620.
Elloso, M.M., H.C. van der Heyde, A. Troutt, D.D. Manning, and W.P. Weidanz. 1996. Human gamma delta T cell subset-proliferative response to malarial antigen in vitro depends on CD4+ T cells or cytokines that signal through components of the IL-2R. J. Immunol. 157:2102.
Elloso, M.M., M. Wallace, D.D. Manning, and W.P. Weidanz. The effects of interleukin-15 on human gd T cell responses to Plasmodium falciparum in vitro. Immunol. Lett. In press.