Research Interest
Pathogenesis and treatment of HIV-induced disorders, gene therapy and immunotherapy of malignant tumors, heat shock proteins, gamma/delta T lymphocytes, immunoregulation, fusion music, good food/drinks, skiing, and tennis.
Training
1976 - M.D., Charles University, Prague, Czechoslovakia
1979 - Ph.D., Charles University, Prague, Czechoslovakia
Publications NCBI PubMed search for "M. Malkovsky"
Fisch, P., Malkovsky, M., Kovats, S., Sturm, E., Braakman, E., Klein, B.S., Voss, S. D., Morrissey, L. W., DeMars, R., Welch, W. J., Bolhuis, R. L. H. & Sondel, P. M.: Recognition by human Vg9/Vd2 T cells of a groEL homolog on Daudi Burkitt's lymphoma cells. Science 250, 1269-1273, 1990.
Bartz, S.R., Hohenwalter, E., Hu, M.-K., Rich, D.H. & Malkovsky, M.: Inhibition of HIV-1 replication by nonimmunosuppressive analogs of cyclosporin A. Proc. Natl. Acad. Sci. USA 92, 5381-5385, 1995.
Poccia, F., Gougeon, M.-L., Agrati, C., Montesano, C., Martini, F., Pauza, C.D., Fisch, P., Wallace, M. & Malkovsky, M.: Innate T-cell immunity in HIV infections: the role of Vg9Vd2 T lymphocytes. Curr. Mol. Med. 2, 485-505, 2002.
Malkovsky, M., Fisch, P., Wallace, M., Sen, A., Mejia, G., Lewis, M., Lisziewicz, J., Lori, F. & Poccia, F.: Gamma/delta T cells: From bench to bedside. Clin. Appl. Immunol. Rev. 3, 235-245, 2003.
McNeel, D.G. & Malkovsky, M.: Immune-based therapies for prostate cancer. Immunol. Letters, 96, 3-9, 2005.
Poccia F., Agrati, C., Martini F., Capobianchi, M.R., Wallace, M. & Malkovsky, M.: Antiviral reactivities of gd T cells. Microbes and Infection 7, 518-528, 2005.
Casetti, R., Perretta, G., Taglioni, A., Mattei, M., Colizzi, V., Dieli, F., D’Offizi G., Malkovsky, M. & Poccia, F.: Drug-induced expansion and differentiation of Vg9Vd2 T cells in vivo: the role of exogenous interleukin-2. J. Immunol. 175, 1593-1598, 2005.