Daniel Muller, M.D., Ph.D. Associate Professor, Department of Medicine, Rheumatology Section Affiliate, Medical Microbiology and Immunology 2605 Medical Sciences Center 1300 University Avenue Madison, WI 53706-1532 (608) 265-2478 Fax: (608) 263-4969 dmuller@wisc.edu

Research Interest

Immunology - Immunogenetics of the major histocompatibility complex (MHC); defining the role of class I MHC and class II MHC-restricted cytotoxic T lympho-cytes in protection and immunopathogenesis in viral and bacterial infections. Neuroendocrine-immune regulation of responses to vaccination.

Training

1973 - A.A., Nassau Community College, Garden City, NY
1975 - B.S., State University of New York, Binghamton, NY
1979 - M.S., University of Wisconsin-Madison, Madison, WI
1981 - Ph.D., University of Wisconsin-Madison, Madison, WI
1985 - M.D., State University of New York, Stony Brook, NY
1987 - 91 - Postdoctoral Fellow, Univ. of North Carolina at Chapel Hill, Chapel Hill, NC

Publications – NCBI PubMed search for "D. Muller"

Muller, D., B. Koller, J.L., Whitton, K. LaPan, K. Brigman, and J.A. Frelinger. 1992. LCMV specific, class II restricted cytotoxic T cells in b2 microglobulin deficient mice. Science 255:1576-1578.

Muller, D., P. Pakpreo, J. Filla, K. Pederson, F. Cigel, and V. Malkovska. 1995. Increased gamma-delta T-lymphocyte response to Mycobacterium bovis BCG in major histocompatibility class I-deficient mice. Infect. Immun. 63:2361-2366.

Muller, D., M. Chen, D. Hildeman, A. Vikingsson, and K. Pederson. 1995. Estrogen influences CD4+ T-lymphocyte activity in vivo and in vitro in b2 microglobulin-deficient mice. Immunol. 86:162-167.

Hildeman, D., M. Salvato, J.L. Whitton, and D. Muller. 1996. Vaccination protects b2 microglobulin deficient mice from immune mediated mortality but not from persisting viral infection. Vaccine 14:1223-1229.

Hildeman, D., D. Yanez, K. Pederson, and D. Muller. 1997. Vaccination against persistent viral infection exacerbates CD4+ T cell mediated immunopathological disease. J. Virol. 71:9672-9678.